Further Reading
External tutorials, methodological papers, and guidance documents that complement the NONMEM Users Guides.
Tutorials
Bauer, R. J. (2019). NONMEM Tutorial Part I: Description of Commands and Options, With Simple Examples of Population Analysis. CPT: Pharmacometrics & Systems Pharmacology, 8(8), 525–537. https://doi.org/10.1002/psp4.12404
Bauer, R. J. (2019). NONMEM Tutorial Part II: Estimation Methods and Advanced Examples. CPT: Pharmacometrics & Systems Pharmacology, 8(8), 538–556. https://doi.org/10.1002/psp4.12422
Nguyen, T. H. T., Mouksassi, M.-S., Holford, N., Al-Huniti, N., Freedman, I., Hooker, A. C., John, J., Karlsson, M. O., Mould, D. R., Pérez Ruixo, J. J., Plan, E. L., Savic, R., van Hasselt, J. G. C., Weber, B., Zhou, C., Comets, E., & Mentré, F. (2021). Tutorial for
$DESIGNin NONMEM: Clinical Trial Evaluation and Optimization. CPT: Pharmacometrics & Systems Pharmacology, 10(12), 1442–1456. https://doi.org/10.1002/psp4.12713Krzyzanski, W., Bauer, R. J., & Dubinsky, S. (2024). Tutorial for Modeling Delays in Biological Systems in the NONMEM Software. CPT: Pharmacometrics & Systems Pharmacology. https://doi.org/10.1002/psp4.70046
Gibiansky, L., & Gibiansky, E. (2012). Tutorial: Numerical (NONMEM) Implementation of the Target-Mediated Drug Disposition Model. In Applied Pharmacometrics, Chapter 8. Wiley. https://doi.org/10.1002/9781119289234.ch8
Methodological papers
Gisleskog, P. O., Karlsson, M. O., & Beal, S. L. (2002). Prior Information for Population Pharmacokinetic and Pharmacokinetic/Pharmacodynamic Analysis: Overview and Guidance with a Focus on the NONMEM PRIOR Subroutine. Journal of Pharmacokinetics and Pharmacodynamics, 29(5), 473–505. https://doi.org/10.1007/s10928-020-09695-z
Gibiansky, L., Gibiansky, E., & Bauer, R. (2012). Comparison of NONMEM 7.2 Estimation Methods and Parallel Processing Efficiency on a Target-Mediated Drug Disposition Model. Journal of Pharmacokinetics and Pharmacodynamics, 39(1), 17–35. https://doi.org/10.1007/s10928-011-9228-y